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Goodman & Gilman 薬理学まとめノート#0 本記事のあらすじ、もくじ(完結済)

本記事は,薬理学のテキスト,というかもはや辞書として有名な"Goodman & Gilman's the Pharmacological Basis of Therapeutics"(和訳:「グッドマン・ギルマン薬理書―薬物治療の基礎と臨床」)についてのまとめを行ったノートである。

テキストの情報(和訳):



記事の形式

はじめに,「何が書いてあるか」と題しそのChapterの要約について箇条書きする。その下に,「ノート」として筆者直筆による手書きのノートを掲載する。


もくじ

-Section Ⅰ "General Principles"

Chapter1 "Drug Invention and the Pharmaceutical Industry"

Chapter2 "Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination"

Chapter3 "Pharmacodynamics: Molecular Mechanisms of Drug Action"

Chapter4"Drug Toxicity and Poisoning"

Chapter5 "Membrane Transporters and Drug Response"

Chapter6 "Drug Metabolism"

Chapter7 "Pharmacogenetics"


-SectionⅡ "Neuropharmacology"

Chapter8 "Neurotransmission: The Autonomic and Somatic Motor Nervous Systems"

Chapter9 "Muscarinic Receptor Agonists and Antagonists"

Chapter10 "Anticholinesterase Agents"

Chapter11 "Nicotine and Agents Acting at the Neuromuscular Junction and Autonomic Ganglia"

Chapter12 "Adrenergic Agonists and Antagonists"

Chapter13 "5-Hydroxytryptamine (Serotonin) and Dopamine"

Chapter14 "Neurotransmission in the Central Nervous System"

Chapter15 "Drug Therapy of Depression and Anxiety Disorders"

Chapter16 "Pharmacotherapy of Psychosis and Mania"

Chapter17 "Pharmacotherapy of the Epilepsies"

Chapter18 "Treatment of Central Nervous System Degenerative Disorders"

Chapter19 "Hypnotics and Sedatives"

Chapter20 "Opioids, Analgesia, and Pain Management"

Chapter21 "General Anesthetics and Therapeutic Gases"

Chapter22 "Local Anesthetics"

Chapter23 "Ethanol"

Chapter24 "Drug Use Disorders and Addiction"


-SectionⅢ"Modulation of Pulmonary, Renal, and Cardiovascular Function"

Chapter25 "Drugs Affecting Renal Excretory Function"

Chapter26 "Renin and Angiotensin"

Chapter27 "Treatment of Ischemic Heart Disease"

Chapter28 "Treatment of Hypertension"

Chapter29 "Therapy of Heart Failure"

Chapter30 "Antiarrhythmic Drugs"

Chapter31 "Treatment of Pulmonary Arterial Hypertension"

Chapter32 "Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs"

Chapter33 "Drug Therapy for Dyslipidemias"


-SectionⅣ"Inflammation, Immunomodulation,and Hematopoiesis"

Chapter34 "Introduction to Immunity and Inflammation"

Chapter35 "Immunosuppressants and Tolerogens"

Chapter36 "Immune Globulins and Vaccines"

Chapter37 "Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor"

Chapter38 "Pharmacotherapy of Inflammation, Fever, Pain, and Gout"

Chapter39 "Histamine, Bradykinin, and Their Antagonists"

Chapter40 "Pulmonary Pharmacology"

Chapter41 "Hematopoietic Agents: Growth Factors, Minerals, and Vitamins"


-SectionⅤ"Hormones and Hormone Antagonists"

Chapter42 "Introduction to Endocrinology: The Hypothalamic-Pituitary Axis"

Chapter43 "Thyroid and Antithyroid Drugs"

Chapter44 "Estrogens, Progestins, and the Female Reproductive Tract"

Chapter45 "Androgens and the Male Reproductive Tract"

Chapter46 "Adrenocorticotropic Hormone, Adrenal Steroids, and the Adrenal Cortex"

Chapter47 "Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia"

Chapter48 "Agents Affecting Mineral Ion Homeostasis and Bone Turnover"


-SectionⅥ"Gastrointestinal Pharmacology"

Chapter49 "Pharmacotherapy for Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease"

Chapter50 "Gastrointestinal Motility and Water Flux, Emesis, and Biliary and Pancreatic Disease"

Chapter51 "Pharmacotherapy of Inflammatory Bowel Disease"


-SectionⅦ"Chemotherapy of Infectious Diseases"

Chapter52 "General Principles of Antimicrobial Therapy"

Chapter53 "Chemotherapy of Malaria"

Chapter54 "Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections"

Chapter55 "Chemotherapy of Helminth Infections"

Chapter56 "Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections"

Chapter57 "Penicillins, Cephalosporins, and Other β-Lactam Antibiotics"

Chapter58 "Aminoglycosides"

Chapter59 "Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents"

Chapter60 "Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy"

Chapter61 "Antifungal Agents

Chapter62 "Antiviral Agents (Nonretroviral)"

Chapter63 "Treatment of Viral Hepatitis (HBV/HCV)"

Chapter64 "Antiretroviral Agents and Treatment of HIV Infection"


-Section Ⅷ"Pharmacotherapy of Neoplastic Disease"

Chapter65 "General Principles in the Pharmacotherapy of Cancer"

Chapter66 "Cytotoxic Drugs"

Chapter67 "Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules"

Chapter68 "Hormones and Related Agents in the Therapy of Cancer"


-Chapter Ⅸ "Special Systems Pharmacology"

Chapter69 "Ocular Pharmacology"

Chapter70 "Dermatological Pharmacology"

Chapter71 "Environmental Toxicology: Carcinogens and Heavy Metals"


注意事項

Q. なんでノートは全部英語なの

A. 筆者の勉強のため(だいたいの言い訳はこれ),生物学と同じ。


Q. このテキストを選んだ意図

A. 薬理学を網羅しているものを選んだつもり,さすがに教科書として使うには大きすぎたが。


Q. 内容が難しすぎる

A. テキストおよび本記事は必ずしも入門レベルを想定していないのは前回同様で,なおかつ必修レベルの域を超えているとは自覚の上で。後日この分野のわかりやすい本を見つけて紹介していきたい。


Q. 何回やるのか

A. 章に合わせて「全71回」の予定。


筆者について:




学習に必要な本を買います。一覧→ https://www.amazon.co.jp/hz/wishlist/ls/1XI8RCAQIKR94?ref_=wl_share