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Status of germline BRCA pathogenic variants in advanced/recurrent pancreatic cancer in Japanese patients
Boursi et al compared outcomes of patients with BRCA1 vs BRCA2-related PDAC using 2 large data sets. The clinical research shows that in patients who were exposed to platinum, BRCA2 pathogenic variants (PVs) were associated with improved su
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Importance of JAMA Pediatrics report on widespread use of COVID-19 vaccination for infants in Japan
Dr. Wee et al. reported in JAMA Pediatrics that study results suggest that completion of a primary mRNA vaccine series provided protection against SARS-CoV-2 infection in children aged 1 through 4 years. Furthermore, Dr. Wee et al. also rep
日本における6か月以上4歳までの乳幼児に対するCOVID-19ワクチン接種の普及におけるJAMA Pediatricsのレポートの重要性
Dr. Weeらは、研究結果は、一次mRNAワクチンシリーズの完了により、1歳から4歳の小児のSARS-CoV-2感染に対する防御が得られたことを示唆しているとJAMA Pediatricsに報告しました。さらに、Dr. Weeらは. 感染症や潜在的な後遺症の予防においてワクチン接種には潜在的な利点があると報告しています。 日本では、2023年9月20日から、生後6か月以上のすべての方に対して、 omicron type SARS-CoV-2 XBB.1.5 variant
Therapy for advanced・recurren・ Castration-resistant prostate cancer by Cancer Genome Medicine in Japan
From December 2019 to April 2023, genetic testing using a cancer genome gene panel will be conducted on 2,991 patients (OncoGuideTM NCC oncopanel test: 679 patients, Foundation One CDx test: 2312 patients) at the Cancer Genome Medicine Depa
Predictive factors for cancer recurrence：the importance of establishing early detection methods for advanced and recurrent malignant tumors using liquid biopsy in Japan
In recent clinical trials, it has been shown that measuring Circulating Tumor DNA spilled into the blood from each malignant tumor is better than the increase in the value of each tumor marker in order to determine the recurrence of various
ウイルス感染性がんの再発予測因子： 日本における、他国でのキッドバイオプシーを用いた進行性・再発性悪性腫瘍の早期検出法の確立の重要性
最近の臨床試験において、各種癌種の再発を早期に判断するために、各腫瘍マーカーの値の上昇よりも、各悪性腫瘍から血液に零れてきたCirculating Tumor DNAを測定する方が優れていることが示されている。 当社の臨床研究チームが実施したこの研究は、2019年12月から2023年4月までに日本の国立大学において2,991人の患者（OncoGuideTM NCCオンコパネル*検査：679名、Foundation One CDx**検査：2312名）を対象にがんゲノム医療に
Benefits of the report reported in JAMA for medical treatment against COVID-19 in Japan
Rubin reported in the JAMA that the new designation, made as part of an August 9 initial risk evaluation of the omicron type SARS-CoV-2 EG.5 subvariant, reflects its “notable rise” in global prevalence during recent weeks. FDA spokesperson
Living-donor Lung Transplantation for COVID-19-Related Lung Injury
On April 7, 2021, a living-donor lung transplantation for lung injury after infection with the SARS-CoV-2 was performed at a national university hospital in Japan. This is the first case of lung transplant surgery for lung injury after infe
Possibility of high tumor-directed immune activation in viral infection-positive malignant tumors
Dr. Tsang E.S. and Dr. Munster P.N. state in the report that oncolytic viruses are of interest not only for their potential to infect tumor cells and by excessive viral replication that induces direct tumor cell death, but also for their ab
