睡眠障害国際分類の診断基準は研究者から支持をされていない。

睡眠障害国際分類（ICSD）は過眠症の研究者から支持を得ていないものです。

睡眠障害国際分類（ICSD）はそもそも出版元すらもその基準に関して否定的な見解を発表しているので当たり前です。

下記に論拠となる引用文献を載せていきます。

 
“I have spoken to a number of clinician-scientists experienced in idiopathic hypersomnia and narcolepsy since the release of the ICSD-3 and there isn’t a lot of confidence in it. Some question whether it is sufficiently justified by data.”

翻訳：ICSD３がリリースされてから、私は特発性過眠症とナルコレプシーの研究に携わる数多くの臨床研究科学者の方々とお話をしてきましたが、ICSD3に対して多くの信頼を示している方はあまりいらっしゃいません。
Hypersomnolence Australia （世界一の特発性過眠症の研究啓発機関）
 
Hypersomnolence Australia, Idiopathic Hypersomnia - A Comprehensive Review 
https://www.hypersomnolenceaustralia.org.au/single-post/2017/12/29/idiopathic-hypersomnia-a-comprehensive-review
 
Rye D, 2013 Narcolepsy Network conference, What’s in a Name? Understanding the Origins of the Terminologies for the Family of Hypersomnias
 
Correspondence with Prof D Rye, 9 May 2015 and 3 August 2017
 
Correspondence with Prof Karel Šonka, 17 August 2015 and 7 August 2017

 
 
“The current ICSD classification, published in 2014, inevitably has important shortcomings, largely reflecting the lack of knowledge about the precise neurobiological mechanisms underlying the majority of sleep disorders we currently delineate. “

翻訳：２０１４年に出版されたICSD3という現在の診断基準についてですが、この診断基準には確実に重大な欠点があります、この診断基準は我々が現在認識をしている主な睡眠障害に潜んでいる正確な神経生物学的メカニズムに関する知識が欠落していることを強く反映する内容となっています。（ICSD３の診断基準改定に関する公式会議録の引用）

Diagnosis of central disorders of hypersomnolence: A reappraisal by European experts. https://doi.org/10.1016/j.smrv.2020.101306

 
 
“These results expand upon data reported by Trotti et al. suggesting a single positive MSLT as defined by ICSD-3 has little diagnostic value as currently defined. “
翻訳：Trotti 氏らのデータを元に展開した結論によると、ICSD３で定義されているMSLT検査が一度だけ陽性であったという結果は現在の定義において、ほとんど診断の価値がないということです。
 
The MSLT is Repeatable in Narcolepsy Type 1 But Not Narcolepsy Type 2: A Retrospective Patient Study
https://doi.org/10.5664/jcsm.6882
 
Trotti LM, Staab BA, Rye DB. Test-retest reliability of the multiple sleep latency test in narcolepsy without cataplexy and idiopathic hypersomnia. J Clin Sleep Med. 2013;9(8):789–795.

下記のAmerican Academy of Sleep Medicine（※ICSDの出版元の団体です）の文献ではMSLT検査上で、特発性過眠症と同じ検査結果になる健常者の方が多くいるため、特発性過眠症の眠気と健常者の眠気との区別は難しいということが記述されています。
 
“This results in significant overlap between mean sleep latency values among healthy controls and populations with excessive sleepiness. Pooled data from normal subjects across all ages using the 4 or 5 nap MSLT with sleep onset defined as the latency to the first epoch of any sleep stage, give a mean sleep latency of 10.4 +/- 4.3 minutes and 11.6 +/- 5.2　minutes, respectively.”
“These papers report a total of 92 patients with idiopathic hypersomnia with a weighted mean sleep latency of 6.2 +/-3.0 minutes. This value is intermediate between those reported for patients with narcolepsy and normal control subjects [6.2.3]. These values suggest that differentiation of sleepiness due to idiopathic hypersomnia from the sleepiness seen in normal controls may be difficult.”
 
Practice Parameters for Clinical Use of the Multiple Sleep Latency Test and the Maintenance of Wakefulness Test An American Academy of Sleep Medicine Report Standards of Practice Committee of the American Academy of Sleep Medicine
https://doi.org/10.1093/sleep/28.1.113
 
6. Fitch K, Bernstein SJ, Aguilar MD, Burnand B, LaCalle JR, Lazaro P, van het Loo M, McDonnell J, Vader JP, Kahan JP. The RAND/UCLA Appropriateness Method User’s Manual. Santa Monica, CA: Rand Corporation, 2001.
 
2. Lavie P. Sleep habits and sleep disturbances in industrial workers in Israel: main findings and some characteristics of workers com- plaining of excessive daytime sleepiness. Sleep 1981; 4:147-158.
 
3. Mitler MM, Carskadon MA, Czeisler CA, Dement WC, Dinges DF, Graeber RC. Catastrophes, sleep, and public policy: consensus report. Sleep 1988;11:100-109.

下記の文献では睡眠障害国際分類第２班（ICSD-２）は自らが自らの結論に対する矛盾したデータを引用していると記載されています。

“There is an assumption that if it (diagnostic criteria, treatment etc) works well for narcolepsy then it will work well for idiopathic hypersomnia despite the authors of the ICSD-2 citing data that actually contradicts their decision. [42]”
 
Hypersoomnolence Australia, Idiopathic Hypersomnia - A Comprehensive Review
https://www.hypersomnolenceaustralia.org.au/single-post/2017/12/29/idiopathic-hypersomnia-a-comprehensive-review
 
42. Trotti, LM, Answers Questions on Diagnostics Relating to Hypersomnia, Hypersomnia Foundation, June 20, 2017
 
 https://note.com/kaminshousupport/n/n0c9969aabf4b