The eien&company Plasma Ion Module system demonstrated the ability to reduce aerosolized SARS-CoV-2 USA-CA1/2020 across all time points when compared to the natural loss rate observed in the controlled setting. The device achieved a 60.48% reduction of active SARS-CoV-2 after 10 minutes, 99.96% after 30 minutes, and reached a 99.998% reduction of active SARS-CoV-2 after 60 minutes of exposure. It should be noted the test was designed to observe the ability of the Plasma Ion Module to reduce pathogens in the air with a fixed airflow in an experimental design. Every effort was made to simulate a real-life environment in the chamber while considering the precautions needed when working with a Biosafety Level 3 pathogen. Furthermore, when aerosolizing and collecting said pathogens, some variables cannot be fully accounted for, namely, placement of pathogen, drop rate, surface saturation, viral destruction upon collection or nebulization, and possibly others. Every effort was made to address these constraints with the design and execution of the trials.