What to look for when buying a pipette tip

The level of accuracy of even the best-certified pipette might be lost if the wrong type of tip is used. Based on the study, the improper type of tip might also make the pipette a source of contamination, result in the waste of valuable samples or chemicals, or even cause people bodily harm in the form of repetitive stress injury. It is important to have sterile pipette tips.

Choosing pipette tips for high accuracy
It is a build quality and safety control challenge, and great build and quality assurance cost money, just like any other manufacturing method. So, avoiding cheap tips and investing in high-quality tips is typically a better approach to ensure that tip variability is kept to a minimum.

If the tip does not correctly fit the pipette, the efficiency of the pipette will suffer. If the pipette base and tip do not have a good seal, the drawn-in air can exit and the right volume of liquid is not inhaled. As a result, the ultimate volume discharged is not quite right. It might be difficult to select a tip that is a suitable match for the pipette.

Two types of pipette tips:
There is the alternative of using the tips sold by the pipette maker if they are provided. However, using high-quality universal tips is frequently the best solution for the pipette and operation.
Such universal tips are compatible with the majority of micropipettes on the market. Generic tips are made to fit snugly and firmly around all pipette barrels, that range somewhat in circumference from one manufacturer to the next.

Filter tips:
Non-barrier and barrier tips, often known as filter tips, are intended for certain applications. Non-barrier tips are intended for general laboratory use. However, if people are going to pipette something which could compromise the pipette, such as flammable, acidic, or greasy substances, people should think about barrier tips to safeguard the pipette and their samples.

Aerosol Barrier tips, also known as filter pipette tips, have a filter within the posterior part of the tip. The filter guards against aerosols and aspirating flammable or thick liquids into the container, which can taint and harm the pipette. These tips are generally pre-sterilized and devoid of DNase/RNase. However, the term "barrier" is a bit misleading for these kinds of suggestions. Only a few high-end tips offer a full sealing barrier. Most filters merely delay the flow of liquid into the pipette chamber.

Non-filter tips:
For many non-sensitive operations, non-filter pipette tips or normal pipette tips can be used. Non-barrier tips are the backbone in any lab and, as an added benefit, are generally the least priced option. These tips are available in bulk, pre-racked, or handy recharges that allow people to reuse the racks while avoiding the discomfort of racking large quantities tips. While most recharges are not sterile pipette tips, they can be sterilised in the autoclave together with their storage containers.